Tick bite encephalitis (TBE) may occur at any time, even outside of specified risk areas. In its most recent publication the renowned Robert Koch Institute in Berlin, Germany, points out that during tick bite season TBE infection should always be taken into account in cases of fever and headache.

EUROIMMUN offers test systems for a reliable diagnosis of anti-TBE antibodies in serum. Intrathecal synthesis can be rapidly detected using the Anti-TBE Virus ELISA for cerebrospinal fluid (CSF). EUROIMMUN also provides an avidity test. The determination of antibody avidity can be very useful in individuals with persisting anti-TBE IgM to rule out acuet infection in suspected cases.

The vaccine Encepur®, which is used most frequently for TBE immunization, is based on antigens of the K23 virus strain. For monitoring successful immunization, EUROIMMUN offers the only currently available Anti-TBE ELISA containing antigens of the K23 vaccine strain and at the same time providing quantification in Vienna units, giving orientation for the evaluation of results.