Molecular Diagnostics

Molecular Diagnostics

EUROArrays in IVD Quality: EUROIMMUN microarrays are based on BIOCHIP Technology. They consist of numerous single-stranded DNA probes with different sequences, which are applied to thin glass at defined positions. Each BIOCHIP consists of 48 DNA sequences, including controls. Each EUROArray slide contains five test fields, enabling up to five samples to be analyzed in parallel.

microarray

Product Highlight – HLA-DQ2/DQ8: The determination of HLA-DQ2/DQ8 is important to exclude Celiac disease as a diagnosis; Celiac disease is an autoimmune disease which occurs in predisposed individuals as a reaction to gluten sensitivity. Almost 100% of Celiac disease patients possess the genetic risk factors HLA-DQ2 or HLA-DQ8.

The EUROArray HLA-DQ2/DQ8 has been specifically designed for the determination of HLA-DQA1 and HLA-DQB1 alleles. It is therefore particularly easy to perform compared to other molecular biological methods for the detection of these alleles – no in-depth molecular biology knowledge is required. The PCR primers in this test system have been optimzed and chosen to that all relevant HLA-DQA1 and HLA-DQB1 alleles are detected. Data analysis, data interpretation and electronic archiving are fully automated using the EUROArrayScan software. The exact analysis of the alpha and beta subunits of the DQ2 and DQ8 molecules ensures reliable and unambiguous results.

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