Products - Infection - Herpes virus infection

Herpes virus infection

Contact our Infectious Disease Team for further details and information

Disease information

The family of herpes viruses is a large family. It includes over 100 virus types, only 8 of which are known to cause infections in humans. These include:

  • Herpes simplex type 1 and 2
  • Varicella zoster virus
  • Epstein Barr virus
  • Cytomegalovirus
  • Human herpes viruses 6 and 7
  • And Human Herpes virus 8 (HHV-8) which causes Kaposi sarcoma.

Despite much similarities in their structure, different herpes infections cause different symptoms. One character however common to all is their ability to persist in the host as a latent state after a primary infection. The latent virus then gets reactivated during immunodeficiency states and causes secondary infection.

Currently, only varicella zoster virus has a vaccine available against it. Adequate management of the infections is important as during pregnancy, these infections can lead to severe damage or even loss of child.

Diagnostic Guidelines

The investigations for a herpes infection include both direct and indirect methods of virus detection. Direct methods employ techniques such as PCR-based assays and cultures using samples from blister liquids, skin, mucosa or bronchoalveolar secretions. Indirect methods look for specific antibodies against the virus in patient’s serum, plasma or CSF. The detection of antibody not only helps diagnose the type of virus but can also contribute in the differentiation of primary infections from recurrent ones.

EUROIMMUN US offers a multitude of diagnostic assays for herpes virus detection including both direct and indirect techniques.

Herpes virus infection products

The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter Substrate Species/ Antigen
626 PCR EURORealTime HSV-1/2
627 IFA antibodies against Herpes simplex virus 1 (HSV-1)
IgG positive control
628 IFA antibodies against Herpes simplex virus 1 (HSV-1)
IgM positive control
629 IFA Herpes simplex virus 1
(HSV-1)
infected cells EU 38
630 IFA HSV-1/HSV-2
negative control
631 WESTERNBLOT antibodies against Herpes simplex virus (HSV)
IgG positive control
632 IFA BIOCHIP Mosaic
HSV-1/HSV-2
2 BIOCHIPs per field:
infected cells
EU 38
633 ELISA CSQ pair of controls
anti-HSV-1/2 Pool (IgG)
634 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
635 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
636 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antibody determination in CSF
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
637 ELISA Herpes simplex virus
(HSV-1/2 Pool)
incl. IgG/RF absorbent
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
638 WESTERNBLOT EUROLINE-WB
Herpes simplex virus 1 (HSV-1)
plus HSV-2 type-specific
glycoprotein G2
Westernblot whole antigen, SDS extract of HSV-1
plus purified gG2
639 ELISA Herpes simplex virus 1 (HSV-1)
incl. IgG/RF absorbent
antigen-coated
microplate wells
native
glycoprotein C1
640 ELISA Herpes simplex virus 1
(HSV-1)
antigen-coated
microplate wells
recombinant
glycoprotein C1
641 IFA antibodies against Herpes simplex virus 2 (HSV-2)
IgG positive control
642 IFA antibodies against Herpes simplex virus 2 (HSV-2)
IgM positive control
643 IFA Herpes simplex virus 2
(HSV-2)
infected cells EU 38
644 ELISA Herpes simplex virus 2 (HSV-2)
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant
glycoprotein G2
645 ELISA Herpes simplex virus 2
(HSV-2)
antigen-coated
microplate wells
recombinant
glycoprotein G2
646 IFA antibodies against HHV-6
IgG positive control
647 IFA antibodies against HHV-6
IgM positive control
648 IFA HHV-6 infected cells EU 30
649 IFA HHV-6 EUROPattern infected cells EU 30
650 IFA HHV-6
negative control
Method Parameter Substrate Species/ Antigen
Contact our Infectious Disease Team for further details and information

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