Autoimmune Diagnostics

Vasculitis

Vasculitis (plural: vasculitides) refers to a heterogeneous group of disorders that are characterized by inflammatory destruction of blood vessels, affecting both arteries and veins. Lymphangitis is sometimes considered a type of vasculitis. Vasculitis is primarily due to leukocyte migration and resultant damage. Although both occur in vasculitis, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities. Some disorders have vasculitis as their main feature. The major types of vasculitis are:

  • Cutaneous small-vessel vasculitis
  • Wegener’s granulomatosis
  • Churg–Strauss syndrome
  • Kawasaki disease
  • Buerger’s disease

There are also many conditions that have vasculitis as an accompanying or atypical symptom, including:

  • Rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and dermatomyositis
  • Cancer, such as lymphomas
  • Infections, such as hepatitis C
  • Exposure to chemicals and drugs, such as amphetamines, cocaine, and anthrax vaccines which contain the Anthrax Protective Antigen as the primary ingredient

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