For research use only. Not for use in diagnostic procedures.
CD163 is a membrane protein that is exclusively expressed on monocytes and macrophages. If these come into contact with inflammation-promoting stimuli such as bacterial molecules, CD163 is enzymatically cleaved off of the immune cell membrane, which results in the formation of soluble CD163 (sCD163). In glomerulonephritis, macrophages invade the tissue. sCD163 enters the urine via Bowman’s capsule, where it can be measured as a biomarker.
For Research Use Only. Not For Use In Diagnostic Procedures.
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determination in urine