Products - Autoimmune - Endocrinology -
Diabetes is one of the most prevalent chronic diseases across the globe. Type 1, also called insulin dependent diabetes mellitus (IDDM), is the result of T-cell mediated destruction of beta cells in the pancreas in genetically predisposed individuals. Moreover, antibodies against various islet cells are formed very early during the course of the disease. These include antibodies against:
The detection of these antibodies also holds great significance in predicting diseases risks in first-degree relatives.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.
wdt_ID | Method | Parameter | Substrate | Species/ Antigen |
---|---|---|---|---|
555 | IFA | islet cells antibodies (PM) EUROPattern pancreas islets |
1 BIOCHIP per field: pancreas |
monkey |
556 | IFA | pancreas islets | pancreas | monkey |
557 | IFA | pancreas islets | pancreas islets (three 1 x 1 mm BIOCHIPs per field) |
monkey |
558 | IFA | pancreas islets, GAD brain: grey and white matter, Purkinje cell cytoplasm (Yo), Hu and Ri antigen |
pancreas cerebellum (2 BIOCHIPs per field) |
monkey monkey |
559 | IFA | antibodies against pancreas islets (islet cell ab control) |
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560 | IFA | antibodies against pancreas islets control with JDF units |
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561 | IFA | antibodies against glutamic acid decarboxylase (GAD ab control) |
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562 | ELISA | GAD | antigen-coated microplate wells |
recombinant glutamic acid decarboxylase (GAD65) |
563 | ELISA | GAD/IA2 Pool | antigen-coated microplate wells |
microplate wells recombinant glutamic acid decarboxylase (GAD65)/ tyrosine phosphatase |
564 | IFA | glutamic acid decarboxylase (GAD) 65 kDa (stiff-person syndrome) |
transfected cells control transfection (2 BIOCHIPs per field) |
EU 90 EU 90 |
565 | ELISA | IA2 | antigen-coated microplate wells |
recombinant tyrosine phosphatase |
566 | RIA | insulin precipitation |
labelled antigen | synthetic product, human |
567 | ELISA | zinc transporter 8 | antigen-coated microplate wells |
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