Products - Autoimmune - Endocrinology - Polyendocrinopathy

Polyendocrinopathy

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Disease information

Polyendocrinopathies are autoimmune diseases characterized by immune mediated destruction of endocrine tissues. They are labelled “poly” because they involve at least two endocrine diseases and one or more antibodies against endocrine organs, parietal cells of the stomach and striated muscles.

Diagnostic Guidelines

Diagnosis is based upon detection of antibodies through indirect immunofluorescence on frozen sections of adrenal cortex, ovary, placenta and testes (for autoantibodies against steroid-hormone producing cells). Moreover, sections of thyroid and parathyroid glands, pancreas and striated muscles enable parallel detection of other associated antibodies, if any.

Polyendocrinopathy products

The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter Substrate Species/ Antigen
591 IFA thyroid gland
(MAb + TAb)
thyroid gland monkey
592 IFA thyroid gland (MAb + TAb)
mitochondria (AMA)
thyroid gland
kidney
(2 BIOCHIPs per field)
monkey
rat
593 IFA Polyendocrinopathy Mosaic
thyroid gland (MAb + TAb)
pancreas islets
adrenal cortex
ovarian antigens
Leydig cells
parietal cells (PCA)

thyroid gland (MAb + TAb)
pancreas islets
adrenal cortex
ovarian antigens
Leydig cells
parietal cells (PCA)
6 BIOCHIPs per field:
thyroid gland
pancreas
adrenal gland
ovary
testis
stomach
monkey
monkey
monkey
monkey
monkey
monkey
594 IFA EUROPLUS
thyroid gland (MAb + TAb)
thyroglobulin (TG)
2 BIOCHIPs per field:
thyroid gland
TG BIOCHIPs
monkey
human
595 IFA antibodies against thyroid microsomes
(MAb control)
596 ELISA thyroid peroxidase
(TPO)
antigen-coated
microplate wells
recombinant, expression with
Baculovirus vector in insect cells
597 RIA thyroid peroxidase (TPO)
coated tubes (CT)
antigen-coated
tubes
native thyroid
peroxidase, human
598 RIA thyroid peroxidase (TPO)
precipitation
labelled antigen native thyroid
peroxidase, human
599 RIA thyroid peroxidase (TPO)
magnetic separation
labelled antigen native thyroid
peroxidase, human
600 IFA antibodies against thyroglobulin
(TAb control)
601 ELISA thyroglobulin
(TG)
antigen-coated
microplate wells
native, human
thyroid gland
602 RIA thyroglobulin (TG)
coated tubes (CT); IRMA
antibody-coated
tubes
native
thyroglobulin
603 RIA thyroglobulin (TG)
coated tubes (CT)
antigen-coated
tubes
native thyroglobulin,
human
604 RIA thyroglobulin (TG)
magnetic separation
labelled antigen native thyroglobulin,
human
605 ELISA TSH receptor
(thyrotropin receptor)
antigen-coated
microplate wells
native,
porcine thyrocytes
606 ELISA TSH receptor
(thyrotropin receptor)
Fast ELISA
antigen-coated
microplate wells
native,
porcine thyrocytes
607 RIA TSH receptor
coated tubes (CT)
antigen-coated
tubes
native TSH receptor,
porcine
608 RIA free triiodothyronine (FT3)
coated tubes (CT)
antibody-coated
tubes
triiodothyronine,
human
609 ELISA reverse triiodothyronine (RT3) antibody-coated
microplate wells
610 RIA free thyroxine (FT4)
coated tubes (CT)
antibody-coated
tubes
thyroxine,
human
611 RIA Turbo thyrotropin (TSH)
coated tubes (CT); IRMA
antibody-coated
tubes
thyrotropin,
human
612 RIA calcitonin
coated tubes (CT); IRMA
antibody-coated
tubes
calcitonin,
human
613 IFA parathyroid gland parathyroid
gland
monkey
614 IFA adrenal cortex adrenal gland monkey
615 IFA Endocrinology Screen (AM) EUROPattern
adrenal cortex
1 BIOCHIP per field:
adrenal gland
monkey
Method Parameter Substrate Species/ Antigen
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