Products - Autoimmune - Endocrinology -
Autoimmune thyroid diseases are characterized by dysregulation of specific immune defenses (B and T cells) and production of antibodies which are predominantly of three types:
Grave’s disease is one of the most common autoimmune diseases in people and the most frequent cause of thyroid hyper-functioning. It can be recognized by a triad of symptoms called Merseburg triad which includes struma, exophthalmos and tachycardia. Another popular autoimmune thyroid disease is Hashimoto thyroiditis which involves progressive destruction of thyroid tissue by T-lymphocytes. So far, there is no absolute cure for Hashimoto thyroiditis. However, treatment aims at reverting the hypothyroid functioning caused by the disease.
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| wdt_ID | Method | Parameter | Substrate | Species/ Antigen |
|---|---|---|---|---|
| 568 | IFA | thyroid gland (MAb + TAb) |
thyroid gland | monkey |
| 569 | IFA | thyroid gland (MAb + TAb) mitochondria (AMA) |
thyroid gland kidney (2 BIOCHIPs per field) |
monkey rat |
| 570 | IFA | Polyendocrinopathy Mosaic thyroid gland (MAb + TAb) pancreas islets adrenal cortex ovarian antigens Leydig cells parietal cells (PCA) |
thyroid gland (MAb + TAb) pancreas islets adrenal cortex ovarian antigens Leydig cells parietal cells (PCA) 6 BIOCHIPs per field: thyroid gland pancreas adrenal gland ovary testis stomach |
monkey monkey monkey monkey monkey monkey |
| 571 | IFA | EUROPLUS thyroid gland (MAb + TAb) thyroglobulin (TG) |
2 BIOCHIPs per field: thyroid gland TG BIOCHIPs |
monkey human |
| 572 | IFA | antibodies against thyroid microsomes (MAb control) |
||
| 573 | ELISA | thyroid peroxidase (TPO) |
antigen-coated microplate wells |
recombinant, expression with Baculovirus vector in insect cells |
| 574 | RIA | thyroid peroxidase (TPO) coated tubes (CT) |
antigen-coated tubes |
native thyroid peroxidase, human |
| 575 | RIA | thyroid peroxidase (TPO) precipitation |
labelled antigen | native thyroid peroxidase, human |
| 576 | RIA | thyroid peroxidase (TPO) magnetic separation |
labelled antigen | native thyroid peroxidase, human |
| 577 | IFA | antibodies against thyroglobulin (TAb control) |
||
| 578 | ELISA | thyroglobulin (TG) |
antigen-coated microplate wells |
native, human thyroid gland |
| 579 | RIA | thyroglobulin (TG) coated tubes (CT); IRMA |
antibody-coated tubes |
native thyroglobulin |
| 580 | RIA | thyroglobulin (TG) coated tubes (CT) |
antigen-coated tubes |
native thyroglobulin, human |
| 581 | RIA | thyroglobulin (TG) magnetic separation |
magnetic separation labelled antigen |
native thyroglobulin, human |
| 582 | ELISA | TSH receptor (thyrotropin receptor) |
antigen-coated microplate wells |
native, porcine thyrocytes |
| 583 | ELISA | TSH receptor (thyrotropin receptor) Fast ELISA |
antigen-coated microplate wells |
native, porcine thyrocytes |
| 584 | RIA | TSH receptor coated tubes (CT) |
antigen-coated tubes |
native TSH receptor, porcine |
| 585 | RIA | free triiodothyronine (FT3) coated tubes (CT) |
antibody-coated tubes |
triiodothyronine, human |
| 586 | ELISA | reverse triiodothyronine (RT3) | antibody-coated microplate wells |
|
| 587 | RIA | free thyroxine (FT4) coated tubes (CT) |
antibody-coated tubes |
thyroxine, human |
| 588 | RIA | Turbo thyrotropin (TSH) coated tubes (CT); IRMA |
antibody-coated tubes |
thyrotropin, human |
| 589 | RIA | alcitonin coated tubes (CT); IRMA |
antibody-coated tubes |
calcitonin, human |
| 590 | ELISA | calcitonin | antibody-coated microplate wells |
synthetic human calcitonin |
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