Products - Autoimmune - Hepatology -
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with progressive destruction of the bile ducts. PSC can exhibit autoantibodies against granulocytes (pANCA) in the serological test; the main target antigen is DNA-bound lactoferrin.
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wdt_ID | Method | Parameter | Substrate | Species/ Antigen |
---|---|---|---|---|
439 | IFA | antibodies against granulocyte cytoplasm, cytoplasmic pattern (cANCA control, PR3 ab control) |
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440 | IFA | cytoplasm of granulocytes (cANCA, pANCA), nuclei of granulocytes (GS-ANA) |
granulocytes, ethanol-fixed |
human |
441 | IFA | cytoplasm of granulocytes (cANCA, pANCA), nuclei of granulocytes (GS-ANA) EUROPattern |
granulocytes, ethanol-fixed |
human |
442 | IFA | antibodies against granulocyte cytoplasm, aliquots from positive control for ANCA diagnostics (10 different fluorescence patterns) |
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443 | ELISA | ANCA Profile (proteinase 3, MPO, elastase, cathepsin G, BPI, lactoferrin separately) |
antigen-coated microplate wells |
native, human neutrophil granulocytes recombinant, human c-DNA expressed in human cell line |
445 | EUROLINE | myeloperoxidase (MPO) proteinase 3 (PR3) |
EUROLINE | |
446 | EUROLINE | positive control serum: IgG, human, 100x concentrated for DL 1200-X G |
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447 | IFA | antibodies against granulocyte cytoplasm, cytoplasmic pattern (cANCA control, PR3 ab control), control serum with indication of titer |
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448 | EUROLINE | myeloperoxidase (MPO) proteinase 3 (PR3) glomerular basement membrane (GBM) |
EUROLINE | |
449 | IFA | granulocytes (cANCA, pANCA) |
granulocytes, formaldehyde-fixed |
human |
450 | IFA | granulocytes (cANCA, pANCA) EUROPattern |
granulocytes, formaldehyde-fixed |
human |
451 | ChLIA | control set Proteinase 3 (PR3) |
||
452 | ChLIA | proteinase 3 (PR3) | ||
453 | IFA | Granulocyte Mosaic 13 EUROPattern cANCA, pANCA, GS-ANA, EUROPattern cell nuclei (ANA), cANCA, pANCA cANCA, pANCA, EUROPattern |
3 BIOCHIPs per field: granulocytes (EOH) HEp-2+granulocytes (EOH) granulocytes (HCHO) |
human human human |
454 | IFA | Granulocyte Mosaic 13 cANCA, pANCA, GS-ANA cell nuclei (ANA), cANCA, pANCA cANCA, pANCA |
3 BIOCHIPs per field: granulocytes (EOH) HEp-2+granulocytes (EOH) granulocytes (HCHO) |
human human human |
455 | IFA | Granulocyte Mosaic 15 EUROPattern cANCA, pANCA, GS-ANA, EUROPattern cell nuclei (ANA), cANCA, pANCA |
2 BIOCHIPs per field: granulocytes (EOH) HEp-2+granulocytes (EOH) |
human human |
456 | IFA | Granulocyte Mosaic 15 cANCA, pANCA, GS-ANA cell nuclei (ANA), cANCA, pANCA |
2 BIOCHIPs per field: granulocytes (EOH) HEp-2+granulocytes (EOH) |
human human |
457 | IFA | Granulocyte Mosaic 17 cANCA, pANCA, GS-ANA cANCA, pANCA cANCA, pANCA cell nuclei (ANA), cANCA, pANCA |
4 BIOCHIPs per field: granulocytes (EOH) granulocytes (HCHO) granulocytes (MOH) HEp-2+granulocytes (EOH) |
human human human human |
458 | IFA | Granulocyte Mosaic 2 EUROPattern cANCA, pANCA, GS-ANA, EUROPattern cANCA, pANCA, EUROPattern |
2 BIOCHIPs per field: granulocytes (EOH) granulocytes (HCHO) |
human human |
459 | IFA | Granulocyte Mosaic 2 cANCA, pANCA, GS-ANA cANCA, pANCA |
2 BIOCHIPs per field: granulocytes (EOH) granulocytes (HCHO) |
human human |
460 | ELISA | cANCA: proteinase 3 (PR3-hn-hr) |
antigen-coated microplate wells |
microplate wells hn: native, human neutrophil granulocytes hr: recombinant, human c-DNA expressed in human cell line |
461 | IFA | EUROPLUS Granulocyte Mosaic 20 cANCA, pANCA, GS-ANA pANCA: myeloperoxidase (MPO) cANCA: proteinase 3 (PR3) |
3 BIOCHIPs per field: granulocytes (EOH) MPO BIOCHIPs PR3 BIOCHIPs |
human |
462 | IFA | EUROPLUS Granulocyte Mosaic 22 cANCA, pANCA, GS-ANA cANCA, pANCA pANCA: myeloperoxidase (MPO) cANCA: proteinase 3 (PR3) |
4 BIOCHIPs per field: granulocytes (EOH) granulocytes (HCHO) MPO BIOCHIPs PR3 BIOCHIPs |
human human |
463 | IFA | EUROPLUS Granulocyte Mosaic 22 EUROPattern cANCA, pANCA, GS-ANA, EUROPattern cANCA, pANCA, EUROPattern pANCA: myeloperoxidase (MPO), EUROPattern cANCA: proteinase 3 (PR3), EUROPattern |
4 BIOCHIPs per field: granulocytes (EOH) granulocytes (HCHO) MPO BIOCHIPs PR3 BIOCHIPs |
human human |
464 | IFA | EUROPLUS Granulocyte Mosaic 25 cANCA, pANCA, GS-ANA cell nuclei (ANA), cANCA, pANCA cANCA, pANCA glomerular basement membrane (GBM) pANCA: myeloperoxidase (MPO) cANCA: proteinase 3 (PR3) |
6 BIOCHIPs per field: granulocytes (EOH) HEp-2+granulocytes (EOH) granulocytes (HCHO) GBM BIOCHIPs MPO BIOCHIPs PR3 BIOCHIPs |
human human human |
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