Products - Autoimmune - Neurology -
Paraneoplastic neurological syndromes (PNS) are diseases of the central and peripheral nervous system that occur in direct association with tumors. However, they are not directly caused by the tumor or by its metastases, nor are they a side-effect of treatment with cytostatic drugs or radiotherapy.
Depending on the type of tumor, tumor cells express antigens such as amphiphysin, CV2/CRMP5, PNMA2 (Ma2/Ta), Ri, Yo, Hu, ZIC4 or Tr (DNER), which can induce the formation of specific autoantibodies. These autoantibodies bind to the respective antigens found in nerve tissue and can thus cause neurological disorders.
For Research Use Only. Not For Use In Diagnostic Procedures.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.
wdt_ID | Method | Parameter | Substrate | Species/ Antigen |
---|---|---|---|---|
626 | IFA | brain: grey and white matter, Purkinje cell cytoplasm (Yo), Hu and Ri antigen CV2, Ma, amphiphysin |
cerebellum | monkey |
627 | EUROLINE | positive control serum: IgG, human, 100x concentrated for DL 1111-1 G, DL 1111-2 G, DL 1111-4 G and DL 1111-7 G |
||
628 | IFA | Neurology Mosaic 1 EUROPattern Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves non-medullated nerves |
3 BIOCHIPs per field: cerebellum nerves intestinal tissue |
monkey monkey monkey |
629 | IFA | Neurology Mosaic 1 Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves non-medullated nerves |
3 BIOCHIPs per field: cerebellum nerves intestinal tissue |
monkey monkey monkey |
630 | IFA | Neurology Mosaic14 cerebellum antigens non-medullated nerves |
2 BIOCHIPs per field: cerebellum non-medullated nerves |
monkey monkey |
631 | IFA | Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves non-medullated nerves cell nuclei (ANA) |
cerebellum nerves intestinal tissue HEp-2 cells (4 BIOCHIPs per field) |
monkey monkey monkey human |
632 | IFA | Neurology Mosaic 17 Yo, Hu, Ri, CV2, Ma, amphiphysin, NMO cerebrum antigens, NMO NMO, optic nerve antigens aquaporin-4 |
5 BIOCHIPs per field cerebellum cerebrum optic nerve transfected cells control transfection |
monkey monkey monkey EU 90 EU 90 |
633 | IFA | Neurology Mosaic 2 Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves |
2 BIOCHIPs per field: cerebellum nerves |
monkey monkey |
634 | EUROLINE | Neuronal Antigens Profile 2 (amphiphysin, CV2, PNMA2 (Ma-2/Ta), Ri, Yo, Hu separately) |
EUROLINE | |
635 | EUROLINE | Neuronal Antigens Profile PLUS RST (amphiphysin, CV2, PNMA2 (Ma-2/Ta), Ri, Yo, Hu, recoverin, SOX1, titin separately) |
EUROLINE | |
636 | EUROLINE | Neuronal Antigens Profile SOX1, titin |
EUROLINE | |
638 | EUROLINE | positive control serum: IgG, human, 100x concentrated for DL 1111-6 G |
||
639 | EUROLINE | Paraneoplastic Neurologic Syndromes - 12 Ag (amphiphysin, CV2, PNMA2 (Ma-2/Ta), Ri, Yo, Hu, recoverin, SOX1, titin, Zic4, GAD65, Tr (DNER) separately) |
EUROLINE | |
640 | IFA | Neurology Mosaic 8 EUROPattern Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves non-medullated nerves pancreas islets |
4 BIOCHIPs per field: cerebellum nerves intestinal tissue pancreas |
monkey monkey monkey monkey |
641 | IFA | Neurology Mosaic 8 Yo, Hu, Ri, CV2, Ma, amphiphysin medullated nerves non-medullated nerves pancreas islets |
4 BIOCHIPs per field cerebellum nerves intestinal tissue pancreas |
monkey monkey monkey monkey |
642 | IFA | antibodies against Delta and Notch-like epidermal growth factor-related receptor (DNER CBA control) |
||
643 | IFA | Delta and Notch-like epidermal growth factor-related receptor (DNER) |
transfected cells control transfection (2 BIOCHIPs per field) |
EU 90 EU 90 |
644 | IFA | antibodies against Purkinje cell cytoplasm (Yo ab control) |
||
645 | IFA | Purkinje Cell Mosaic 1 Yo/CDR2 DNER ITPR1 CARP |
4 BIOCHIPs per field: transfected cells transfected cells transfected cells transfected cells |
EU 90 EU 90 EU 90 EU 90 |
646 | IFA | antibodies against neuronal nuclei: Ri antigen (Ri ab control) |
||
647 | IFA | antibodies against neuronal nuclei: Hu antigen (Hu ab control) |
||
648 | IFA | zinc finger protein ZIC4 | transfected cells control transfection (2 BIOCHIPs per field) |
EU 90 EU 90 |
2024 EUROIMMUN US
Privacy Policy | Website Terms and Conditions | Cookie Notice and Settings | Sitemap