Products - Infection - Tick-borne infections

Tick-borne infections

Contact our Infectious Disease Product Team for further details and information

Disease information

Ticks can transmit various pathogens like bacteria, viruses and parasites while taking a blood meal. Lyme disease is a very popular tick-borne infection that is caused by Borrelia. Other pathogens that can be transmitted via ticks include:

  • TBE virus
  • Crimean Congo fever virus
  • Rickettsia
  • Babesia
  • Coxiella

Tick-borne infections come with a multitude of symptoms and that mainly depend upon the causative pathogen. These infections can involve the skin, the joints and even the central nervous system. Moreover, they can range from mild subclinical infections and severe life-threatening conditions. Since, vaccines are only available against a limited number of pathogens, the most effective treatment approach remains exposure prophylaxis.

Diagnostic Guidelines

Like most other infectious diseases, diagnostics for tick-borne infections involve both direct and indirect methods. Direct methods include blood smears, pathogen cultures and PCR-based assays; indirect methods revolve around detection of antibodies formed against the pathogens in blood and CSF. For cases where suitable samples can not be obtained or the amount of pathogen in the sample is very low, antibody testing is the method of choice.

We at EUROIMMUN offer a broad spectrum of serological tests to detect antibodies in suspected tick-borne infections including ELISA, ChLIA and various immunoblots.

Tick-borne infections products

The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter Substrate Species/ Antigen
37 IFA antibodies against Borrelia afzelii/B. burgdorferi/B. garinii/OspC
IgM positive control
38 IFA antibodies against Borrelia afzelii/B. burgdorferi/B. garinii/VlsE
IgG positive control
39 IFA Borrelia afzelii/B. burgdorferi/B. garinii
negative control
40 EUROLINE EUROLINE Borrelia-RN-AT
(OspC Bg native, OspC Bb native,
OspC Ba native, p39, VlsE Bb separately)
EUROLINE
41 EUROLINE EUROLINE Borrelia-RN-AT
(p18, p19, p20, p21, p58,
OspC (p25), p39, p83, LBb, LBa,
VlsE Bg, VlsE Bb, VlsE Ba separately)
EUROLINE
42 EUROLINE positive control serum: IgG, human, 50x concentrated
for Borrelia
43 EUROLINE positive control serum: IgM, human, 50x concentrated
for Borrelia
44 WESTERNBLOT antibodies against Borrelia afzelii
IgG positive control
(Westernblot/EUROLINE-WB)
45 WESTERNBLOT antibodies against Borrelia afzelii
IgM positive control
(Westernblot/EUROLINE-WB)
46 WESTERNBLOT Borrelia afzelii Westernblot whole antigen, SDS extract of
Borrelia afzelii
47 WESTERNBLOT EUROLINE-WB
Borrelia
Westernblot whole antigen, SDS extract of
Borrelia afzelii plus VlsE
48 EUROLINE EUROLINE Borrelia-RN-AT-adv
(OspC-adv Bsp, OspC-adv Bg, OspC-adv
Bb, OspC-adv Ba, p39, VlsE Bb separately)
EUROLINE
49 IFA Borrelia
burgdorferi
(CH)

burgdorferi
(CH)
bacterial
smear
verification BIOCHIP
(2 BIOCHIPs per field)
Borrelia
burgdorferi
(CH)
50 ELISA Borrelia
incl. IgG/RF absorbent
antigen-coated
microplate wells
whole antigen, detergent extracts of
Borrelia burgdorferi sensu stricto,
Borrelia garinii and Borrelia afzelii
51 WESTERNBLOT antibodies against Borrelia burgdorferi
IgG positive control
52 WESTERNBLOT antibodies against Borrelia burgdorferi
IgM positive control
53 WESTERNBLOT Borrelia burgdorferi Westernblot whole antigen, SDS extract of
Borrelia burgdorferi sensu stricto
54 ChLIA Borrelia recombinant OspC
55 ChLIA Borrelia recombinant VlsE,
recombinant DbpA
56 ChLIA control set
Borrelia
57 ELISA Borrelia burgdorferi
VlsE
antigen-coated
microplate wells
recombinant VlsE from
Borrelia burgdorferi sensu stricto
58 ELISA Borrelia
plus VlsE
antigen-coated
microplate wells
whole antigen, detergent extracts of
Borrelia burgdorferi sensu stricto,
Borrelia garinii and Borrelia afzelii
plus recombinant VlsE from
Borrelia burgdorferi sensu stricto
59 ELISA Lyme ELISA antigen-coated
microplate wells
recombinant VlsE from
Borrelia burgdorferi sensu stricto
and Borrelia OspC
60 ELISA Borrelia Select: recombinant
antigens with OspC advanced
antigen-coated
microplate wells
mixture of specific recombinant
Borrelia antigens incl. dimere
OspC advanced
61 ELISA Borrelia Select: recombinant
antigens with VlsE
antigen-coated
microplate wells
mixture of specific recombinant
Borrelia antigens incl. VlsE
Method Parameter Substrate Species/ Antigen
Contact our Infectious Disease Product Team for further details and information

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