Over the past years, the global spread of many new viruses and other pathogens has been observed. The associated diseases are called “emerging infectious diseases”. This term refers to infectious diseases that occur for the first time in a population or have increased rapidly in incidence or regional distribution. Viruses transmitted by arthropods, also known as arboviruses, are among the most common causative agents of diseases in humans worldwide and have posed a growing problem over the past decades. Arboviruses have a great ability to mutate and adapt, which is why they often cause outbreaks. Important examples are dengue and chikungunya fever as well as Zika fever, which spread to large parts of South America in 2015/2016. However, also in moderate climates – like in Europe – arboviruses such as West Nile virus and chikungunya virus have caused seasonal outbreaks in the past. The clinical courses of diseases caused by arboviruses are very similar, so that diagnosis cannot be based on the clinical picture alone.
In addition to the before-mentioned arboviruses, there are various other pathogens that cause large outbreaks and could develop into a significant global health problem, such as SARS-CoV-2, which led to a pandemic.
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wdt_ID | Method | Parameter | Substrate | Species/ Antigen |
---|---|---|---|---|
708 | IFA | MERS-CoV, SARS-CoV negative control |
||
709 | IFA | SARS coronavirus | infected and non- infected cells (2 BIOCHIPs per field) |
EU 14 |
710 | IFA | MERS coronavirus | infected and non- infected cells (2 BIOCHIPs per field) |
EU 14 |
711 | ELISA | MERS coronavirus | antigen-coated microplate wells |
recombinant S1 antigen of MERS coronavirus (MERS-CoV S1) |
712 | ELISA | SARS-CoV-2 | antigen-coated microplate wells |
recombinant S1 antigen of SARS-CoV-2 |
713 | PCR | EURORealTime SARS-CoV-2 | ||
714 | ELISA | SARS-CoV-2 NCP | ||
715 | IFA | antibodies against TBE virus (TBEV) IgG positive control |
||
716 | IFA | antibodies against TBE virus (TBEV) IgM positive control |
||
717 | IFA | TBE virus (TBEV) | infected and non- infected cells (2 BIOCHIPs per field) |
EU 14 |
718 | IFA | TBE virus (TBEV) negative control |
||
719 | ELISA | TBE virus | antigen-coated microplate wells |
TBE viral proteins (strain "K23") |
720 | ELISA | TBE virus incl. IgG/RF absorbent |
antigen-coated microplate wells |
TBE viral proteins (strain "K23") |
721 | IFA | antibodies against Flaviviruses IgG positive control |
||
722 | IFA | Flavivirus Mosaic 1 TBE virus (TBEV) West Nile virus (WNV) Japanese encephalitis virus (JEV) Yellow fever virus (YFV) |
4 BIOCHIPs per field: infected cells infected cells infected cells infected cells |
EU 14 EU 14 EU 14 EU 14 |
723 | IFA | Flaviviruses negative control |
||
724 | ELISA | TBE virus avidity determination |
antigen-coated microplate wells |
TBE viral proteins (strain "K23") |
725 | IFA | Flavivirus Profile 2 upper row: TBE virus (TBEV) West Nile virus (WNV) Japanese encephalitis virus (JEV) Yellow fever virus (YFV) bottom row: Dengue virus types 1 - 4 (DENV) |
infected cells infected cells infected cells infected cells infected cells |
EU 14 EU 14 EU 14 EU 14 EU 14 |
726 | IFA | Flavivirus Mosaic 3 TBE virus (TBEV) West Nile virus (WNV) Japanese encephalitis virus (JEV) Yellow fever virus (YFV) Dengue virus types 1 - 4 (DENV) |
9 BIOCHIPs per field: infected cells infected cells infected cells infected cells infected cells non-infected cells |
EU 14 EU 14 EU 14 EU 14 EU 14 EU 14 |
727 | ELISA | CSQ pair of controls anti-TBE virus Vienna (IgG) |
||
728 | ELISA | TBE virus Vienna |
antigen-coated microplate wells |
TBE viral proteins (strain "K23") |
729 | ELISA | CSQ pair of controls anti-TBE virus (IgG) |
||
730 | ELISA | CSQ pair of controls anti-TBE virus (IgM) |
||
731 | ELISA | TBE virus antibody determination in CSF |
antigen-coated microplate wells |
TBE viral proteins (strain "K23") |
732 | IFA | antibodies against West Nile virus (WNV) IgG positive control |
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