Products - Infection - Herpes virus

Herpes virus

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Information

The family of herpesviruses encompasses more than 100 different virus types, eight of which can cause infections in humans. These so-called human herpesviruses encompass herpes simplex virus of type 1 and 2 (HSV-1 and -2), varicella zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesviruses 6 and 7 (HHV-6 and -7) as well as human herpesvirus 8 (HHV-8), which is associated with Kaposi sarcoma.

Diagnostic Guidelines

Despite great structural similarities of the different pathogens, herpesvirus infection can cause very different diseases, e.g. cold sores or genital herpes, chickenpox, shingles, kissing disease or different cancers. During pregnancy, especially primary infection with particular herpesviruses may lead to severe damage or even loss of the child. There is currently only a vaccine against VZV. After primary infection, which often proceeds asymptomatically, herpesviruses persist life-long in the body in a latent state and may become reactivated at a later time point, e.g. due to a weakened immune system, and (again) cause symptoms.

Laboratory diagnostics of herpesviruses is based on direct or indirect detection methods. Direct methods, which are especially relevant for diagnostics of acute infections or in immunosuppressed persons include, e.g. virus culture or PCR-based tests, in which viral nucleic acids are detected. Blister liquid, skin or mucosal smears, blood, CSF or broncoalveolar lavage fluid is used as sample material. If the herpesvirus specific antibody is detected in patient serum, plasma or CSF, this is considered as indirect pathogen detection. The antibody detection not only allows conclusions to be drawn on which virus is present in the patient, but can also contribute to the differentiation of primary and recurrent infections. EUROIMMUN offers a broad spectrum of products for the detection of herpesvirus infections, including both antibody detection and direct detection methods.

Herpes virus products

For Research Use Only. Not For Use In Diagnostic Procedures.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter Substrate Species/ Antigen
626 PCR EURORealTime HSV-1/2
627 IFA antibodies against Herpes simplex virus 1 (HSV-1)
IgG positive control
628 IFA antibodies against Herpes simplex virus 1 (HSV-1)
IgM positive control
629 IFA Herpes simplex virus 1
(HSV-1)
infected cells EU 38
630 IFA HSV-1/HSV-2
negative control
631 WESTERNBLOT antibodies against Herpes simplex virus (HSV)
IgG positive control
632 IFA BIOCHIP Mosaic
HSV-1/HSV-2
2 BIOCHIPs per field:
infected cells
EU 38
633 ELISA CSQ pair of controls
anti-HSV-1/2 Pool (IgG)
634 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
635 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
636 ELISA Herpes simplex virus
(HSV-1/2 Pool)
antibody determination in CSF
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
637 ELISA Herpes simplex virus
(HSV-1/2 Pool)
incl. IgG/RF absorbent
antigen-coated
microplate wells
native antigens
from HSV-1 and HSV-2
638 WESTERNBLOT EUROLINE-WB
Herpes simplex virus 1 (HSV-1)
plus HSV-2 type-specific
glycoprotein G2
Westernblot whole antigen, SDS extract of HSV-1
plus purified gG2
639 ELISA Herpes simplex virus 1 (HSV-1)
incl. IgG/RF absorbent
antigen-coated
microplate wells
native
glycoprotein C1
640 ELISA Herpes simplex virus 1
(HSV-1)
antigen-coated
microplate wells
recombinant
glycoprotein C1
641 IFA antibodies against Herpes simplex virus 2 (HSV-2)
IgG positive control
642 IFA antibodies against Herpes simplex virus 2 (HSV-2)
IgM positive control
643 IFA Herpes simplex virus 2
(HSV-2)
infected cells EU 38
644 ELISA Herpes simplex virus 2 (HSV-2)
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant
glycoprotein G2
645 ELISA Herpes simplex virus 2
(HSV-2)
antigen-coated
microplate wells
recombinant
glycoprotein G2
646 IFA antibodies against HHV-6
IgG positive control
647 IFA antibodies against HHV-6
IgM positive control
648 IFA HHV-6 infected cells EU 30
649 IFA HHV-6 EUROPattern infected cells EU 30
650 IFA HHV-6
negative control
Method Parameter Substrate Species/ Antigen
table.wpDataTable { table-layout: fixed !important; } table.wpDataTable td, table.wpDataTable th { white-space: normal !important; } /* buttons background color */ .wpDataTables .wdt-checkbox-filter.btn, .wdt-frontend-modal .btn, div.dt-button-collection a.dt-button.active:not(.disabled), div.dt-button-collection button.dt-button.active:not(.disabled) { background-color: #3eb44a !important; background-image: none !important; } /* buttons border color */ .wpDataTables .wdt-checkbox-filter.btn, .wdt-frontend-modal .btn:not(.dropdown-toggle), div.dt-button-collection a.dt-button.active:not(.disabled), div.dt-button-collection button.dt-button.active:not(.disabled) { border: 1px solid; border-color: #ffffff !important; } /* buttons font color */ .wpDataTables .wdt-checkbox-filter.btn, .wpDataTables .selecter .selecter-selected, .wdt-frontend-modal .btn:not(.dropdown-toggle), div.dt-button-collection a.dt-button.active:not(.disabled), div.dt-button-collection button.dt-button.active:not(.disabled) { color: #ffffff !important; } /** buttons background hover color */ .wpDataTables .wdt-checkbox-filter.btn:hover, .wdt-frontend-modal .btn:not(.dropdown-toggle).btn:hover, div.dt-button-collection a.dt-button.active:not(.disabled):hover, div.dt-button-collection button.dt-button.active:not(.disabled):hover { background-color: #ffffff !important; background-image: none !important; } /** buttons hover border color */ .wpDataTables .wdt-checkbox-filter.btn:hover, .wdt-frontend-modal .btn:not(.dropdown-toggle).btn:hover, div.dt-button-collection a.dt-button.active:not(.disabled):hover, div.dt-button-collection button.dt-button.active:not(.disabled):hover { border-color: #3eb44a !important; } /** buttons hover font color */ .wpDataTables .wdt-checkbox-filter.btn:hover, .wdt-frontend-modal .btn:not(.dropdown-toggle).btn:hover, div.dt-button-collection a.dt-button.active:not(.disabled):hover, div.dt-button-collection button.dt-button.active:not(.disabled):hover { color: #3eb44a !important; } /** buttons hover font color */ .wpDataTables .wdt-checkbox-filter.btn:hover, .wdt-frontend-modal .btn:not(.dropdown-toggle).btn:hover, div.dt-button-collection a.dt-button.active:not(.disabled):hover { color: #3eb44a !important; } /* table font size */ .wpdt-c.wpDataTablesWrapper table.wpdtSimpleTable, .wpdt-c .wpDataTablesWrapper table.wpDataTable { font-size:17px !important; }
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