Products - Infection - Pregnancy Relevant

Pregnancy-relevant

Contact our Infectious Disease Product Team for further details and information

Information

The term TORCH encompasses all infectious agents that can be transferred from mother to child in the uterus, during birth or after birth via vertical infection. It includes Toxoplasma gondii, rubella virus, cytomegalovirus (CMV), herpes simplex virus (HSV) and other pathogens such as Chlamydia trachomatis, parvovirus B19, Treponema pallidum and varicella zoster virus (VZV).

Diagnostic Guidelines

Analysis of antibodies against TORCH parameters is an essential part of pre-, peri- and postnatal care. The tests allow the immune status of the mother to be established and the risks to an existing pregnancy assessed. TORCH tests are generally performed during the first trimester of pregnancy, but they can also be carried out on the newborn if an infection is suspected. The initial investigation of antibodies against TORCH pathogens is aimed at determining the immune status of the mother in order to be able to differentiate between acute primary and past infections or reactivations during the course of pregnancy. If diagnosed early, TORCH infections can in part be effectively treated, reducing the risk of birth defects or loss of the fetus.

Primary infections during pregnancy are especially feared since they are associated with an increased risk of damage to the child.

Pregnancy-relevant products

For Research Use Only. Not For Use In Diagnostic Procedures.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter Substrate Species/ Antigen
166 IFA antibodies against Treponema pallidum
unspecific FTA IgG positive control
167 IFA antibodies against Treponema pallidum
unspecific FTA IgM positive control
168 IFA Treponema pallidum
(FTA-ABS)
bacterial
smear
verification BIOCHIP
(2 BIOCHIPs per field)
T. pallidum
169 IFA Treponema pallidum
FTA negative control
170 ELISA Treponema pallidum antigen-coated
microplate wells
recombinant antigens
15 kDa, 17 kDa, 47 kDa,
42 kDa (TmpA)
171 ELISA Treponema pallidum
incl. IgG/RF absorbent
antigen-coated
microplate wells

microplate wells
recombinant antigens
15 kDa, 17 kDa, 47 kDa,
42 kDa (TmpA)
172 ELISA Treponema pallidum
Screen ELISA
antigen-coated
microplate wells
recombinant antigens
15 kDa, 17 kDa, 47 kDa,
42 kDa (TmpA)
173 EUROLINE positive control serum: IgG, human, 50x concentrated
for Treponema pallidum
174 EUROLINE positive control serum: IgM, human, 50x concentrated
for Treponema pallidum
175 EUROLINE Treponema pallidum
(TpN15, TpN17, TmpA, TpN47 separately)
EUROLINE
176 WESTERNBLOT antibodies against Treponema pallidum
IgG positive control
177 WESTERNBLOT antibodies against Treponema pallidum
IgM positive control
178 WESTERNBLOT Treponema pallidum Westernblot 15 kDa, 17 kDa,
45 kDa (tmpA), 47 kDa
179 IFA antibodies against Treponema pallidum
IgG positive control for FTA absorption
180 WESTERNBLOT EUROLINE-WB
Treponema pallidum
plus cardiolipin
Westernblot 15 kDa, 17 kDa, 45 kDa (tmpA), 47 kDa
plus purified cardiolipin
181 ELISA CSQ pair of controls
anti-Treponema pallidum (IgG)
182 ELISA Treponema pallidum
antibody determination in CSF
antigen-coated
microplate wells
recombinant antigens
15 kDa, 17 kDa, 47 kDa,
42 kDa (TmpA)
183 IFA Treponema pallidum
(FTA-ABS)
bacterial
smears
verification BIOCHIP
(3 BIOCHIPs per field)
T. pallidum
T. phagedenis
184 IFA antibodies against Chlamydia trachomatis
IgA positive control
185 IFA antibodies against Chlamydia trachomatis
IgG positive control
186 IFA antibodies against Chlamydia trachomatis
IgM positive control
187 IFA Chlamydia
trachomatis
infected cells EU 40
188 ELISA Chlamydia trachomatis antigen-coated
microplate wells
native MOMP antigen
from C. trachomatis
189 ELISA Chlamydia trachomatis antigen-coated
microplate wells
native MOMP antigen
from C. trachomatis
190 ELISA Chlamydia trachomatis
incl. IgG/RF absorbent
antigen-coated
microplate wells
native MOMP antigen
from C. trachomatis
Method Parameter Substrate Species/ Antigen
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