Products - Molecular genetic - Molecular genetics - HLA-Cw6 Direct

HLA-Cw6 Direct

Contact our Molecular Genetic Product Team for further details and information


HLA-C*06 alleles are the genetic component for the predisposition to the autoimmune reactions that result in psoriasis. Recent total-genome association studies have confirmed that of all gene sites HLA-C shows the highest association with psoriasis, and HLA-C*06 can be considered by far the most powerful genetic marker for the disease. The determination of HLA-C*06 is of great significance since the presence of the HLA-Cw6 antigen is associated in particular with type 1 psoriasis vulgaris (OR 16.0) and psoriasis guttata (OR 33.6), but only is comparatively weakly associated (OR 2.6) with type 2 psoriasis vulgaris. Type 1 psoriasis vulgaris has a more severe course than type 2 psoriasis vulgaris.

Diagnostic Guidelines

The EUROArray HLA-Cw6 Direct has been specifically designed for the determination of HLA-C*06 alleles. It is therefore particularly easy to perform compared to other molecular biological methods for the detection of HLA-C*06. In this test system the PCR primers have been chosen and optimized so that all relevant HLA-C*06 subtypes are detected.

HLA-Cw6 Direct products

For Research Use Only. Not For Use In Diagnostic Procedures.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.

wdt_ID Method Parameter
768 EUROArray EUROArray HLA-Cw6
769 EUROArray EUROArray HLA-Cw6
with QIAamp DSP Blood Mini Kit
DNA purification
Method Parameter
Contact our Molecular Genetic Product Team for further details and information
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