Bone is a living organ that is continuously being remodeled. When bone breakdown exceeds bone formation, osteoporosis develops, leaving bones brittle and more likely to fracture—even under minor stress. While most common in post-menopausal women, osteoporosis is underdiagnosed in men and women, alike. With age being a major risk factor, it is estimated that 1 in 2 women and 1 in 5 men aged 50 and older in the US will suffer from an osteoporosis-related fracture. Bone turnover markers are used by clinicians to guide treatment decisions in the management of osteoporosis—monitoring response to therapy, identifying non-compliance, and predicting rates of bone loss and fracture risk.
Dr. Paul D. Miller, MD, FACP
Medical Director, Colorado Center for Bone Health, Distinguished Clinical Professor of Medicine, University of Colorado Medical Center
Dr. Jennifer Kelly, DO, FACE, CCD
Director, Metabolic Bone Program, University of Vermont Medical CenterChief, Division of Endocrinology and Diabetes, University of Vermont Health NetworkProfessor, Larner College of Medicine
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